In 1970 ALfred POngratz (nickname ALPO) founded his company in Auerbach i.d.OPf.
In 2000, the former location was expanded.
In 2005, ALPO Technik Medical Products GmbH & Co. KG was founded.
In 2008, the second location in the Lohe Süd industrial area in Auerbach i.d.OPf was opened.
In 2012 and 2013, the second site was modernised in order to merge the two operating sites at the Lohe Süd industrial area in Auerbach i.d.OPf.
In 2019, ALPO was integrated into a group of Bavarian medical products and pharmaceutical companies.
In 2021, ALPO was renamed ALPO Medizintechnik GmbH.